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Rockefeller University Bioinformatics Specialist, Host-Pathogen Interaction in New York, New York

Job: IRC24954

Description

Job Title Bioinformatics Specialist, Host-Pathogen Interaction

Laboratory / Department Host-Pathogen Biology

Department Description

Our lab has developed novel CRISPR-based tools for functional genomics in the globally important pathogen, Mycobacterium tuberculosis . At Rockefeller, you will join a dynamic research team to investigate the mechanisms that enable this bacterium to cause disease and evade current antibiotics, with the long-term goal of developing new strategies to improve control of this pandemic.

Detailed Description

The Bioinformatics Specialist will contribute to the laboratory's research on tuberculosis, with the long-term goal of developing new strategies to improve control of the disease. The Bioinformatics Specialist will be responsible for the implementation of established next generation sequencing (NGS) data analysis pipelines, as well as the design, development, and implementation of custom NGS data analysis pipelines. Responsibilities include high-throughput genomics approaches to study tuberculosis pathogenesis, including analysis of CRISPR-based genome scale screens, single cell RNA sequencing, RNAseq, TNseq, and microbial genomics. Will utilize commonly used algorithms for alignment, assembly, variant calling, and differential expression/count analysis. The Bioinformatics Specialist will collaborate with laboratory members and will have the opportunity to lead independent research projects. Will interact extensively with both the vibrant NYC tuberculosis research community as well as the Rockefeller Bioinformatics Resource Core.

Job Requirements

Bachelor's degree and a minimum of 2 years of bioinformatics experience required; Master's degree or PhD. in bioinformatics, computational biology, statistics, computer science or related field preferred. Must have experience managing and working with next generation sequencing data, as well as extensive knowledge and experience in the use of existing bioinformatics tools and biological databases. Proficiency in Python and R required, and one or more programming languages such as Perl, Java, or C/C++ desirable. Must have experience working in Linux and running tasks in a cluster environment. Must have experience working in teams centered around an important question.

Additional Details

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans

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