Rockefeller University Research Assistant, Chromatin Biology and Epigenetics in New York, New York
Job Title Research Assistant, Chromatin Biology and Epigenetics
Laboratory / Department Chromatin Biology and Epigenetics
The fundamental structure of chromatin suggests that all DNA-templated processes, including a wide range of epigenetic phenomena, are influenced by chromatin alterations with far-reaching implications for human biology and disease. Research in Dr. Allis' laboratory is centered on chromatin and its regulation though post-translational modification of histone (and non-histone) proteins, ATP-dependent remodeling of chromatin, and the exchange of histone variants.
The Research Assistant will contribute directly to work by a physician scientist who specializes in medical oncology. This work will focus on understanding the fundamental epigenetic mechanisms of cancer-associated mutations. Projects may also involve preclinical drug development of anticancer therapeutics. Responsibilities include recording data, analyzing results, performing experiments with cell in tissue culture, and maintaining inventory of frozen cell stocks. Will practice research techniques focused on cell culture, generation of cell lines harboring tumor-derived mutations, cell-based chromatin assays (eg. ChIP, DNA methylation and/or produce next-generation sequencing libraries), measurements of small molecule activity, and cellular differentiation assays.
Bachelor's degree in science required; Master's degree in biology or other life science preferred. Previous experience with cell culture, molecular biology and biochemical techniques preferred. Must have excellent written and oral communication skills. Must be self-motivated, inquisitive, ambitious, and comfortable working as part of a team in a fast-paced environment.
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans