Research Assistant | Laboratory of Human Genetics and Infectious Diseases in New York, NY
The Laboratory of Human Genetics of Infectious Diseases studies the genetics of human predisposition to pediatric infectious diseases, particularly mycobacterial diseases, invasive pneumococcal diseases, and herpes simplex encephalitis. It aims to identify Mendelian 'holes' in the immune defense of otherwise healthy children who are susceptible to specific infectious diseases, work that has profound implications for and has resulted in a paradigm shift in human clinical medicine and fundamental immunology. In the past decade, the laboratory has uncovered that single genetic lesions in children confer severe and selective vulnerability to certain illnesses, whereas corresponding infections in adults result more from polygenetic inheritance. This work not only blurs the distinction between patient-based Mendelian genetics and population-based complex genetics but has also provided experimental support for a unified theory of human infectious diseases.
The Research Assistant will be assisting a research team, consisting of one associate professor and four PhD students or post-doc, studying human genetics and immunological basis of severe viral diseases.
Job responsibilities include:
• Being in charge of generating and keep records of plasmids expressing cDNA of various human genes carrying different variations.
• Performing routine biochemical and immunological assays related to antiviral immune responses in various cell types mainly human fibroblasts and monocytic cell lines.
• Providing technical support to specific projects of the team related to studies of SARS-CoV-2 related multi-system inflammatory syndrome in children (MIS-C).
Bachelor's degree required. Master's degree in science or at least 2 years of relevant experience is preferred. An educational emphasis in biochemistry, cell biology, immunology, virology or a related field
is preferred. Must be detail oriented, have a strong sense of responsibility and be able to work as part of a team in a fast-paced environment. Strong interpersonal and communication skills, and computer proficiency are required. Experience with tissue culture and molecular biology preferred.
Compensation Range: Min
Compensation Range: Max
Job Locations US-NY-New York
Position Type Regular Full-Time