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Rockefeller University Research Assistant, Molecular Immunology in New York, New York

Job: IRC24574


Job Title Research Assistant, Molecular Immunology

Laboratory / Department Molecular Immunology

Department Description

We pursue a combination of biochemical, molecular and genetic approaches to define the checkpoints that regulate B cell development, antibody production and B cell tolerance. A second area of interest is in dendritic cells. Our interests range from the earliest phases of the B cell pathway, including the commitment to becoming a B cell through the completion of maturation. Our ongoing work includes a focus on mechanisms of V(D)J recombination, somatic mutation, isotype switching, allelic exclusion and tolerance.

Detailed Description

The Laboratory has conducted a series of first-in-humans studies with two of the most promising broadly neutralizing anti-HIV-1 antibodies: 3BNC117 and 10-1074. Both antibodies are being developed for potential roles in HIV-1 prevention and therapy. The Research Assistant will evaluate the safety, pharmacokinetics, and antiviral activity of these promising new immunotherapeutic investigational products. Will be responsible for exploring the effects of these antibodies on the HIV-1 reservoir and on host immune responses, when given alone or in combination with latency.

Job Requirements

Bachelor's degree in science required; educational emphasis in biology preferred. Previous lab experience desired. Must be detail-oriented, a hard worker, and have excellent organizational skills. Knowledge of basic lab and sterile techniques necessary. Must be a team-player who can work independently and perform repetitive tasks with accuracy and precision. May be required to work flexible hours, including some weekends.

Additional Details

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans