Rockefeller University Research Assistant in New York, New York

Department Description

Apoptosis (programmed cell death) is essential for metazoan development. We study apoptosis in the nematode C. elegans, and are interested in understanding cues that regulate apoptosis during development. To this end we have used genetic strategies to identify cell-specific apoptosis regulators. The remarkable conservation of the apoptotic machinery suggests that our studies will yield insight into the regulation of mammalian apoptosis. Glia account for 90 percent of the cells in the human brain, yet compared to their neuronal counterparts little is known about their development, function and morphogenesis. C. elegans contains 24 neuron-associated cells that are strikingly similar to vertebrate glia. We are interested in understanding how these cells develop, acquire their morphologies and regulate neuronal activity. We are using laser ablation, time-lapse microscopy, genomic and genetic approaches to address these issues.

Detailed Description

The Research Assistant will contribute to studies surrounding the process of linker cell deaths in C. elegans. Will perform genetic and microscopy studies as well as molecular biology experiments.

Job Requirements

Bachelor's degree in science required. Previous laboratory experience and experience studying C. elegans preferred. Molecular biology experience very helpful.

Job Title: Research Assistant

Laboratory / Department: Developmental Genetics

Job: IRC21414

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