Rockefeller University Research Assistant in New York, New York

Job Title Research Assistant

Laboratory / Department Neurogenetics and Behavior

Department Description

The Lab seeks to understand how an animal's behavior is guided by integrating sensory input with information about its internal physiological state. The group studies this problem in the Aedes aegypti mosquito, a vector for Zika, Dengue, Chikungunya, and Yellow Fever. For a female mosquito to complete egg development, the insect requires a blood meal. Acquiring that blood from a human is an innate behavior that potentially spreads dangerous infectious diseases carried by the insect. The Lab has developed CRISPR/Cas9 genome-editing tools , which allows the team to apply a genetic approach to understanding how female mosquitoes integrate sensory cues such as body odor, heat, and exhaled carbon dioxide to hunt their human hosts. The group is currently pursuing a number of questions: Why are some people more attractive to mosquitoes than others? How do insect repellents work? How are multiple sensory cues integrated in the mosquito brain to elicit innate behaviors? How do female mosquitoes select a body of water suitable for egg laying? This work provides insights into potential methods to control mosquitoes' biting behavior.

Detailed Description

Working with students and postdocs, the Research Assistant will design and generate mutant and transgenic mosquitoes using CRISPR and other innovative transgenic techniques. The Research Assistant will perform molecular biology experiments, molecular and fluorescent genotyping, and strain maintenance. Possibility for additional opportunities for mentored and independent project development using these genetic reagents.

Job Requirements

Bachelor's degree in science required; educational emphasis in neuroscience, chemistry, molecular biology, or biochemistry preferred. Previous bench experience and familiarity working with mosquitoes preferred. Must be ambitious, independent, and interested in playing a central role in a long-term research program. Must have strong attention to detail, patience, motivation, and excellent interpersonal skills. Excellent organizational and communication skills required. Must be flexible, self-directed, and able to self-organize an individual schedule to efficiently manage multiple projects from beginning to end.

Additional Details

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans