Rockefeller University Research Assistant in New York, New York
Job Title Research Assistant
Laboratory / Department Molecular and Cellular Neuroscience
The Laboratory of Molecular and Cellular Neuroscience studies the molecular defects responsible for neurological and psychiatric disorders including Alzheimer's disease, major depressive disorder, Parkinson's disease, and obsessive compulsive disorder, as well as the molecular mechanisms by which neuro- and psychoactive drugs produce their pharmacological actions in these disorders. Research from the laboratory has demonstrated that most neurotransmitters and neuromodulators achieve their actions and interactions on post-synaptic neurons through a process called "slow synaptic transmission." This process involves activation of highly complex signal transduction cascades. For the last 10 years, the group has applied this knowledge and developed a state-of-the-art methodologies (eg. BacTRAP), to the study of the molecular pathways behind various neurological and psychiatric disorders.
The Research Assistant will be involved in the biochemistry and evaluation of small molecules in cells and in animal models at the interface of chemistry and biology. The Research Assistant will work on in vitro assay development, perform high throughput screening, perform Western blotting, cell culture, plasmid purification, PCR, ELISA, mouse genotyping and maintain mouse colonies. Will also be responsible for routine lab maintenance, operation of various scientific apparatus, and compiling, processing and analyzing data.
Bachelor's degree in science required; educational emphasis in biochemistry, biology, or neuroscience preferred. Must have knowledge of laboratory procedures, including biochemical terminology, cell culture, Western blot, PCR and ELISA. Experience with assay development, drug screening, in vitro and in vivo evaluation of compounds, and animal colony maintenance preferred. Must be willing to work with small animals. Must also possess strong verbal and written communication skills and attention to detail.
The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans