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Rockefeller University Research Assistant in New York, New York

Job: IRC26829


Job Title Research Assistant

Laboratory / Department Developmental Genetics

Department Description

Apoptosis (programmed cell death) is essential for metazoan development. We study apoptosis in the nematode C. elegans, and are interested in understanding cues that regulate apoptosis during development. To this end we have used genetic strategies to identify cell-specific apoptosis regulators. The remarkable conservation of the apoptotic machinery suggests that our studies will yield insight into the regulation of mammalian apoptosis. Glia account for 90 percent of the cells in the human brain, yet compared to their neuronal counterparts little is known about their development, function and morphogenesis. C. elegans contains 24 neuron-associated cells that are strikingly similar to vertebrate glia. We are interested in understanding how these cells develop, acquire their morphologies and regulate neuronal activity. We are using laser ablation, time-lapse microscopy, genomic and genetic approaches to address these issues.

Detailed Description

Under the mentorship of a Postdoctoral Scholar, the Research Assistant will contribute to ongoing projects within the Laboratory. Responsibilities include genetic crosses, genotyping (PCR, agarose gel electrophoresis, DNA sequence analysis), creating transgenic C. elegans strains (including DNA cloning), and analyzing gene expression using fluorescence microscopy and image analysis.

Job Requirements

Bachelor's degree in science required; educational emphasis in genetics and cell biology preferred. Prior research with C. elegans is a plus. Candidates with experience in genetics, molecular biology, and fluorescence microscopy are especially encouraged to apply. Must be highly motivated and driven by scientific curiosity, possess excellent verbal, written, and electronic communication skills, and the ability to interact effectively in a collaborative work environment. Must have excellent organizational skills, including laboratory record keeping, data management, and prioritizing work to carry out complex experiments with extreme attention to detail. Previous independent research experience or extensive laboratory coursework is strongly preferred. Must be amenable to changing work schedules that prioritize experiments and which often deviate from the standard 9 to 5 workday, occasionally including weekend hours.

Additional Details

This job requires that employees be fully vaccinated against COVID-19 as a condition of employment. Rockefeller University provides reasonable accommodations where legally required including accommodations for medical conditions and sincerely held religious beliefs.

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans