Rockefeller University Research Assistant in New York, New York
Job Title Research Assistant
Laboratory / Department Neuroendocrinology
We take an integrated, interdisciplinary approach in our work, combining behavioral analysis and measurements of hormone levels with neurochemical, morphological, neuro- pharmacological, cellular and molecular methodologies. Studies are under way to investigate cellular and molecular mechanisms underlying the effects of stress and sex hormones on neurogenesis, synaptogenesis and dendritic remodeling in the hippocampal region of the adult brain.
The Research Assistant will be involved in the study of sex differences in stress-related neuropsychiatric disorders. Will acquire experience working with transgenic BDNF Val66Met mice, an animal model carrying a human single nucleotide polymorphism associated with genetic susceptibility to psychiatric disorders. In particular, the Research Assistant will contribute towards a project designed to elucidate the effects of stress and ovarian hormones on behavior and neuroarchitecture in mice, as well as whole-genome analysis. Responsibilities include husbandry and maintenance of a colony of transgenic mice, performing behavioral tests and analysis, analyzing neuronal architecture via Golgi staining, performing RT-qPCR, immunocytochemistry, Western blots, ELISA, and in-situ hybridization, and bioinformatics and whole-genome sequencing.
Bachelor's degree in science required. Must be highly motivated, possess a strong interest in behavioral neuroscience, and be comfortable working with rodents. Familiarity with biochemistry and molecular biology techniques necessary.